Junk DNA- Very Important for the Survival of Mammals

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what is junk DNA

About half of our DNA is written as junk. Surrounding or broken genes, viruses that are stuck in our genome. Also isolated or silenced, none of which is relevant to the evolution of the human organism.

Studies over the past decade have shown that this genetic “dark matter” has some function. Initially controlling the expression of host genes – only 2% of our total genome – that code for proteins.

Biologists continue to debate. These regulatory sequences of DNA play essential or harmful roles in the body or are mere phenomena. It is an accident that an organism can live without.

junk DNA

This is the first example of a piece of “junk DNA” for the survival of mammals.

Studies have shown that at least one transposition family. Ancient viruses that have invaded our genome by millions. Probably plays an important role in all mammals. When the researchers threw a certain transposition into the rats, half of their rats died before the baby was born.

A new study led by researchers at the University of California, Berkeley and the University of Washington explores an element of this junk DNA called ‘transposition’, which allows selfish DNA sequences to invade their host genome.

In rats, this transposition controls the proliferation of early fertilized embryonic cells and the time of implantation in the mother’s uterus. The researchers looked at seven more mammal species, including humans. They found the regulatory components of the virus related to cell proliferation and embryo implantation. Which suggests that mammals have been domesticated independently of ancient viral DNA to play an important role in the development of early embryos.

According to senior author Lin Hare, UC Berkeley professor of molecular and cell biology, the study highlights a neglected driver of evolution. Viruses that integrate into our genomes and re-establish themselves as regulators of host genes.

Rats and humans share 99% of their protein coding genes in their genomes. He said we are very similar to each other.

What’s the difference between rats and humans?

One of the main differences is gene control. Rats and humans have the same genes, but they may be regulated differently. Transposons have the potential to generate lots of gene-regulating diversity and can help us understand species-specific differences in the world.junk DNA

The real significance of this story is that it tells us how evolution works in the most unexpected way. Transposons have long been regarded as useless genetic material. They make up such a large part of the mammalian genome. Many interesting studies explain that transposons are the driving force behind the evolution of the human genome. Yet, this is the first instance where deleting a piece of junk DNA leads to a deadly phenotype, which shows that the work of certain transposons may be essential.

This finding may have implications for human infertility. According to author Andrew Modzalewski, a UC Berkeley postdoctoral fellow, about half of all human abortions are not diagnosed. They do not have clear genetic material. Could transposons be involved according to this?

If 50% of our genomes are non-coding or repetitive-these dark objects কারণ it is tempting to question whether the causes of human reproduction and human infertility can be explained by junk DNA sequences.

 

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So-Called Junk DNA – Genetic “Dark Matter” – Is Actually Critical to Survival in Mammals

 

 

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